How SKYRIZI
Works

How does SKYRIZI work?

Plaque psoriasis on your skin actually starts inside your body. While the exact cause is unknown, an overactive immune system could be a source. SKYRIZI has been designed to work with your immune system, attaching to a specific protein that can cause inflammation. By attaching to this protein, SKYRIZI helps reduce the inflammation inside the body that leads to plaques on the skin.

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How long do you spend managing your psoriasis symptoms every day?

How long do you spend managing your psoriasis symptoms every day?

Discussing how long you spend managing your symptoms can help your doctor understand your overall treatment goals and help you both make decisions about your treatment plan. If you want to get the conversation started and are looking for a dermatologist, you can start here.

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SKYRIZI works in the immune system

SKYRIZI is a biologic designed to be similar to proteins found within your own immune system. It specifically attaches to a protein called IL-23, one of the proteins that may contribute to inflammation and plaque psoriasis.

Inflammation Icon

The good and bad of inflammation

One of the ways your immune system protects you is with inflammation. However, too much inflammation can mean your immune system is overactive. That’s what happens with plaque psoriasis.

Il23 Protein Imbalance SKYRIZI

A protein imbalance

While the exact cause of plaque psoriasis is unknown, your body may produce too much of a protein called IL-23. IL-23 is one of several proteins that may contribute to excess inflammation inside the body, which can lead to painful, red, itchy, burning plaques on the skin.

Il23 SKYRIZI Protein

What SKYRIZI does

This is where SKYRIZI comes in. SKYRIZI works by attaching to excess IL-23. This can help reduce the inflammation inside the body that leads to plaques on the skin.